© 2007 European Society of Cardiology
Uric acid as a prognostic marker in acute heart failure — new expectations from an old molecule
Divison of Applied Cachexia Research, Department of Cardiology, Charité Medical School, Campus Virchow Hospital Augustenburger Platz 1, 13353 Berlin, Germany wolfram.doehner@charite.de
Department of Clinical Cardiology, National Heart and Lung Institute, Imperial College London, UK
* Corresponding author. Tel.: +49 30 450 553507; fax: +49 30 450 553951.
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Heart failure is one of the most prominent clinical diagnoses in modern medicine, be it from the clinical, prognostic, epidemiological or socio-economic point of view. In times of flow-chart guided diagnostic and therapeutic decision trees there is a growing need for diagnostic tools to objectively channel our options as early as possible. Accordingly, a growing number of markers and indicator parameters have been evaluated to assess disease status and putative further disease development. Nearly every month another parameter or assessment method is reported to contribute to the estimation of heart failure status and progression. These markers are becoming increasingly costly, complex to obtain or to interpret and most of them may never make it into the everyday clinical setting.
Recently, an increasing interest
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