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European Journal of Heart Failure 2006 8(2):203-207; doi:10.1016/j.ejheart.2005.03.008
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© 2006 European Society of Cardiology

Predictors of exercise capacity and everyday activity in older heart failure patients

Miles D. Withama,*, Ishbel S. Argoa, Derek W. Johnstonb, Allan D. Struthersc and Marion E.T. McMurdoa

a Section of Ageing and Health, University of Dundee, Ninewells Hospital Dundee DD1 9SY, UK
b School of Psychology, University of Aberdeen Aberdeen, UK
c Department of Clinical Pharmacology, University of Dundee, Ninewells Hospital Dundee DD1 9SY, UK

* Corresponding author. Tel.: +44 1382 632436; fax: +44 1382 660675. E-mail address: m.witham{at}dundee.ac.uk


  Abstract

Background: Exercise capacity and daily activity are key outcomes for older, frail heart failure patients. Little is known about the determinants of these outcomes in this patient group.

Aims: To explore predictors of exercise capacity and daily activity in older, frail heart failure patients.

Methods: Analysis of prospectively collected data from a cohort of 82 patients aged 70 years and over, enrolled in a randomised controlled trial of exercise in heart failure patients. Pathophysiological, demographic, psychological and social factors were analysed by multivariate regression to determine predictors of exercise capacity (6-min walk distance) and daily activity (daily accelerometer counts).

Results: Between 49% and 55% of the variance in 6-min walk distance was explained by variables including New York Heart Association class, depression score, attitude to ageing and use of walking aids. Only 11% to 26% of the variance in accelerometer scores was explained by the model; 6-min walk distance was the only consistent predictor of daily activity.

Conclusions: Physical, psychological and attitudinal variables contribute to variance of the 6-min walk. Six-minute walk distance predicts a small amount of the variance in daily activity, but the majority of variance in daily activity remains unexplained and requires further investigation.

Key Words: Aged • Heart failure Congestive • Exercise capacity • Daily activity

Received October 4, 2004; Accepted March 3, 2005


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