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European Journal of Heart Failure 2005 7(7):1164-1167; doi:10.1016/j.ejheart.2005.03.003
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© 2005 European Society of Cardiology

B-type natriuretic peptide in patients with sepsis and preserved left ventricular ejection fraction

Micha Maedera,*, Peter Ammanna, Wolfgang Kiowskib and Hans Ricklia

a Department of Internal Medicine, Division of Cardiology, Hospital of St. Gallen Rorschacherstrasse 95 CH-9007 St. Gallen, Switzerland
b Klinik im Park, HerzGefässzentrum, Zürich, Switzerland

* Corresponding author. Tel.: +41 71 494 11 11; fax: +41 71 494 61 42. E-mail address: micha.maeder@kssg.ch

Key Words: B-type natriuretic peptide • Left ventricular ejection fraction • Congestive heart failure • Sepsis • Systemic inflammatory response syndrome • Acute respiratory distress syndrome

Received May 22, 2004; Accepted March 3, 2005

The first 10% of the full text of this article appears below.

B-type natriuretic peptide (BNP) as a marker of left ventricular end-diastolic pressure [1] has proven to be a useful diagnostic tool to differentiate dyspnea caused by congestive heart failure (CHF) from non-cardiac dyspnea in patients presenting at the emergency room [2,3]. It has been demonstrated that a normal BNP level (<80 to 100 pg/mL) has a high negative predictive value to exclude CHF [2,3], whereas a markedly elevated BNP has a high positive predictive value for CHF [4]. Therefore, BNP testing seems to be very useful not only for emergency room settings, but also for the intensive care unit (ICU), where a rapid assessment of the cause of a patient's worsening oxygenation is required. However, while introducing BNP testing in our ICU we have observed surprisingly high BNP levels in critically ill patients with echocardiographically preserved left ventricular . . . [Full Text of this Article]


   1. Methods
 

   2. Results
 

   3. Discussion
 

   4. Study limitations
 

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