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European Journal of Heart Failure 2004 6(6):749-752; doi:10.1016/j.ejheart.2003.11.005
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© 2004 European Society of Cardiology

NT-proBNP: a marker for successful myocardial reperfusion in AMI patients treated with primary percutaneous coronary intervention

Jaap-Ronald Bloma, Arnoud W.J. van ‘t Hofa, Jose P.S. Henriquesa, J. Hans Geertmana, Robbert Slingerlandb and Jan C.A. Hoorntjea,*

a Isala Klinieken, location De Weezenlanden, Department of Cardiology Groot Wezenland 20, 8011 JW Zwolle, The Netherlands
b Isala Klinieken, location De Weezenlanden, Department of Clinical Chemistry Groot Wezenland 20, 8011 JW Zwolle, The Netherlands

* Corresponding author. Tel.: +31-38-4242374; fax: +31-38-4243222. E-mail address: v.derks@diagram-zwolle.nl

Key Words: NT-proBNP • Acute myocardial infarction • Percutaneous coronary intervention

Received May 7, 2003; Revised October 1, 2003; Accepted November 13, 2003

The first 10% of the full text of this article appears below.


   1. Background
 
The cardiac natriuretic peptide system is activated in left ventricular (LV) dysfunction and has been evaluated in patients after acute myocardial infarction (AMI) [1–3].

Higher levels of BNP and NT-proBNP in the first few days after AMI is a powerful predictor of LV dysfunction, prognosis in heart failure and death [4–8].

In patients with AMI, early restoration of antegrade flow in the infarct-related artery reduces infarct size and LV dysfunction, improving both short- and long-term outcome [9,10].

Accordingly, BNP kinetics could reflect the success . . . [Full Text of this Article]


   2. Aims
 

   3. Methods
 

   4. Results
 

   5. Conclusion
 

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