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European Journal of Heart Failure 2004 6(4):433-438; doi:10.1016/j.ejheart.2003.08.002
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© 2004 European Society of Cardiology

European reference values for Doppler indices of left ventricular diastolic filling{star}

M.F.Victor Sima, Shu F. Hob, M.Sinead O'Mahonyc,*, John A. Stewardd, Maurice Buchaltere and Michael Burrf

a Llandough Hospital Penarth, UK
b Royal Shrewsbury Hospital Shropshire, UK
c University of Wales College of Medicine, Llandough Hospital Penarth, UK
d Welsh Cancer Intelligence and Surveillance Unit Cardiff, UK
e Department of Cardiology, University Hospital of Wales Cardiff, UK
f Department of Epidemiology, Statistics and Public Health, University of Wales College of Medicine Cardiff, UK

* Corresponding author. Present address: University Department of Geriatric Medicine, 3rd Floor, Academic Centre, Llandough Hospital, Penlan Road, Penarth CF64 2XX, UK. Tel.: +44-29-2071-6986; fax: +44-29-2071-1267. E-mail address: omahonyms{at}cf.ac.uk


  Abstract

The European Study Group on diastolic heart failure requires objective evidence of abnormal left ventricular diastolic function to establish the diagnosis of diastolic heart failure, which is common in older people. Reference values for Doppler indices of transmitral flow, used to assess left ventricular diastolic function, have not been reported for people 70 years and over in Europe. The aim of this study was to establish reference values for these Doppler indices of transmitral flow in older people. A random sample of 355 subjects aged 70 and over, living in the community underwent clinical assessment and echocardiography. Asymptomatic subjects with no cardiovascular disease and cardiovascular risk factors were identified. Measurements of five commonly used Doppler indices of transmitral flow from these subjects were obtained and reference range expressed as mean±2 standard deviations and as percentiles. We have therefore generated reference Doppler values of transmitral flow for people aged over 70 in a British population.

Key Words: Heart failure • Echocardiography • Diastolic parameters • Old age • Reference range

Received September 2, 2002; Revised July 7, 2003; Accepted August 28, 2003

{star} This work was undertaken in the Department of Geriatric Medicine, University of Wales College of Medicine, Llandough Hospital, Penarth.


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