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European Journal of Heart Failure 2003 5(1):23-25; doi:10.1016/S1388-9842(02)00117-4
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© 2002 European Society of Cardiology

Plasma concentrations of interleukin-2 soluble receptor in mild ischaemic left ventricular dysfunction

Antonio Abbatea, Elena Vecileb, Nicola Fiottic, Carlo Giansantec, Gianfranco Guarnieric, Germano Di Sciasciod and Aldo Dobrinab,*

a Institute of Cardiology, Catholic University of the Sacred Heart Rome, Italy
b Department of Physiology and Pathology, University of Trieste Via Fleming 22, Trieste, 34127 Italy
c Department of Clinical Medicine, University of Trieste Trieste, Italy
d Department of Cardiovascular Sciences University Campus Bio-Medico of Rome, Rome, Italy

* Corresponding author. Fax: +39-040-567862 E-mail address: dobrina@univ.trieste.it

Key Words: Inflammation • Immune system • Heart failure • Myocardial ischaemia

Received November 19, 2001; Revised February 13, 2002; Accepted March 26, 2002

The first 10% of the full text of this article appears below.


   1. Background
 
Inflammation is increasingly thought to play a key role in promoting coronary atherosclerosis [1]. Inflammatory markers, such as C-reactive protein (CRP) have been found to be elevated in patients with acute coronary syndromes and to be predictive of adverse cardiac events [2–5]. Similarly, increased levels of inflammatory cytokines have been shown in congestive heart failure [6] (CHF) and follow the progression of the disease to its terminal phases [7] (end-stage CHF). Whether activation of the inflammatory-immune system is induced in the early phases of ischaemic left ventricular dysfunction (LVD) remains to be determined.


   2. Aim of the study
 
In the present study, we evaluated plasma levels of the prototypical acute phase protein CRP, . . . [Full Text of this Article]


   3. Methods
 

   4. Results
 

   5. Conclusion
 

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