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European Journal of Heart Failure 2008 10(7):722-723; doi:10.1016/j.ejheart.2008.05.005
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© 2008 European Society of Cardiology

Is exercise efficiency really impaired in heart failure patients?

Lindsay M. Edwards, Simon A. Jobson and Graham J. Kemp

Cardiac Metabolism Research Group, Department of Physiology, Anatomy and Genetics, University of Oxford Parks Road, Oxford OX1 3PT, UK E-mail address: lindsay.edwards@dpag.ox.ac.uk. Tel.: +44 1865 282 253.
Department of Sports Studies, University of Winchester Winchester, UK
School of Clinical Science, Faculty of Medicine, University of Liverpool Liverpool, UK

The first 10% of the full text of this article appears below.

Witte et al. [1] recently reported reduced exercise efficiency in patients with chronic heart failure. Theoretically, this could occur because of mitochondrial uncoupling [2] or increased cost at any point downstream of the mitochondrion. However, we question their interpretation.

In an individual, metabolic . . . [Full Text of this Article]


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