© 2008 European Society of Cardiology
Towards a systematic scientific approach in the assessment of efficacy of an herbal preparation: Hawthorn (Crataegus spp.)
Team Elucidate, Department of Chemistry, Cork Institute of Technology Bishopstown, Cork, Co. Cork, Ireland E-mail address: ambrose.furey@cit.ie (A. Furey).
* Corresponding author. Tel.: +353 87 9116110; fax: +353 21 4345191.
Key Words: Crataegus Hawthorn SPICE trial Treatment
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Crataegus spp. (Hawthorn) is a genus composed of nearly 300 species. Evidence exists of man's use of hawthorn as a food source from as early as the late Iron Age [1]. The name hawthorn is in fact thought to be an Anglo-Saxon name: the Anglo-Saxon being haegthorn [2]. Hawthorn (Crataegus spp.), belongs to the Rosaceae family and consists of small, deciduous, fruit bearing trees and shrubs with thorny branches. The plant species has been utilised medicinally worldwide. It is notable that the medicinal use of hawthorn in the treatment of conditions relating to the cardiovascular system is comparable globally. The 1633 edition of John Gerard's Herbal states that hawthorn berries are very astringent and used to stay the laske, the menses and all other fluxes of bloud [3]. Recorded evidence of folk use also reflects its astringent properties, coupled with some uses relating to the cardiovascular