© 2006 European Society of Cardiology
Levosimendan and plasma BNP levels: Do inflammatory cytokines regulate BNP in chronic decompensated heart failure?
Department of Medical Imaging, St. Vincent's Hospital Melbourne, Australia
* Corresponding author. E-mail address: reperfusion@hotmail.com
Received September 18, 2005;
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We read with interest the recent study by Moertl et al. [1]. In this study the investigators demonstrated that in chronic decompensated heart failure patients, therapeutic PGE1 as opposed to levosimendan produced a sustained reduction in plasma B-type natriuretic peptide (BNP) levels. This finding suggests that PGE1 would be superior to levosimendan in treating decompensated heart failure on the basis of a