© 2006 European Society of Cardiology
Effects of exercise training on cardiac performance, exercise capacity and quality of life in patients with heart failure: A meta-analysis
a Department of Physical Therapy, VU University Medical Center De Boelelaan 1118, 1081 HV Amsterdam, The Netherlands
b Department of Rehabilitation Medicine, University Medical Centre Heidelberglaan 100, 3508 GA Utrecht and Institute for Fundamental and Clinical Human Movement Sciences, The Netherlands
* Corresponding author. Department of Physical Therapy, VU University Medical Centre, De Boelelaan 1118, PO Box 7057, 1007 MB Amsterdam, The Netherlands. Tel.: +31 20 4440466; fax: +31 20 40469. E-mail address: baf.vantol{at}vumc.nl
 |
Abstract |
|---|
Background: Despite major advances in pharmacological treatment of chronic heart failure (CHF), a number of patients still suffer from dyspnoea, fatigue, diminished exercise capacity and poor quality of life. It is in this context that exercise training is being intensively evaluated for any additional benefit in the treatment of CHF.
Aims: To determine the effect of exercise training in patients with CHF on cardiac performance, exercise capacity and health-related quality of life. A meta-analysis was performed to obtain this goal.
Methods and results: After including 35 randomised controlled trials, the methodological quality of each study was assessed, summary effect sizes (SESs) and the concomitant 95% confidence intervals (95% CI) were calculated for each outcome. Quantitative analysis showed statistically significant SESs, at rest, for diastolic blood pressure and end-diastolic volume. During maximal exercise, significant SESs were found for systolic blood pressure, heart rate, cardiac output, peak oxygen uptake, anaerobic threshold and 6-min walking test. The Minnesota Living with Heart Failure Questionnaire improved by an average of 9.7 points.
Conclusions: Exercise training has clinically important effects on exercise capacity and HRQL, and may have small positive effects on cardiac performance during exercise.
Key Words: Heart failure • Exercise • Physical fitness • Quality of life • Meta-analysis
Received October 30, 2005; Revised January 4, 2006; Accepted February 27, 2006
CiteULike 
Connotea 
Del.icio.us What's this?
This article has been cited by other articles:
|
|
 |
|
  L. Wevers, I. van de Port, M. Vermue, G. Mead, and G. Kwakkel Effects of Task-Oriented Circuit Class Training on Walking Competency After Stroke: A Systematic Review Stroke, July 1, 2009; 40(7): 2450 - 2459. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. Y. Patwala, P. R. Woods, L. Sharp, D. F. Goldspink, L. B. Tan, and D. J. Wright Maximizing Patient Benefit From Cardiac Resynchronization Therapy With the Addition of Structured Exercise Training: A Randomized Controlled Study J. Am. Coll. Cardiol., June 23, 2009; 53(25): 2332 - 2339. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 K. Jolly, R. S. Taylor, G. Y.H. Lip, M. Davies, R. Davis, J. Mant, S. Singh, S. Greenfield, J. Ingram, J. Stubley, et al. A randomized trial of the addition of home-based exercise to specialist heart failure nurse care: the Birmingham Rehabilitation Uptake Maximisation study for patients with Congestive Heart Failure (BRUM-CHF) study Eur J Heart Fail, February 1, 2009; 11(2): 205 - 213. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. A. Rubin Exercise Training in Heart Failure: Contradictory or Conventional? J. Am. Coll. Cardiol., June 19, 2007; 49(24): 2337 - 2340. [Full Text] [PDF]
|
|
|
|
|
|
M. J. Haykowsky, Y. Liang, D. Pechter, L. W. Jones, F. A. McAlister, and A. M. Clark A Meta-Analysis of the Effect of Exercise Training on Left Ventricular Remodeling in Heart Failure Patients: The Benefit Depends on the Type of Training Performed J. Am. Coll. Cardiol., June 19, 2007; 49(24): 2329 - 2336. [Abstract] [Full Text] [PDF]
|
|