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European Journal of Heart Failure 2003 5(3):217-227; doi:10.1016/S1388-9842(03)00008-4
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© 2003 European Society of Cardiology

The non-invasive assessment of hibernating myocardium in ischaemic cardiomyopathy—a myriad of techniques

Gavin I.W. Galasko and Avijit Lahiri*

Department of Cardiovascular Medicine, Northwick Park Hospital Watford Road, Harrow, Middlesex HA1 3UJ, UK

* Corresponding author. Tel.: +44-20-8869-2547/8; fax: +44-20-8864-0075. E-mail address: nph{at}cardiac-research.org


  Abstract

Heart failure is placing an ever-increasing burden on society. Many subjects with heart failure and underlying coronary artery disease have a significant amount of akinetic but viable myocardium that is able to contract should myocardial perfusion improve (hibernating myocardium). Non-randomised studies have shown prognostic benefit in subjects with hibernating myocardium undergoing revascularisation. Several non-invasive techniques have been developed to assess the presence or absence of hibernating myocardium. This review will examine the epidemiology and underlying pathogenesis of hibernating myocardium; evaluate the non-invasive techniques for diagnosing hibernating myocardium, and look at therapeutic intervention in subjects with hibernating myocardium.

Key Words: Heart failure • Coronary artery disease • Hibernating myocardium • Non-invasive imaging

Received November 12, 2001; Revised July 17, 2002; Accepted September 25, 2002


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